The Faroes statement: Human Health effects of developmental exposure to chemicals in our environment

Philippe Grandjean, David Bellinger, Åke Bergman, Sylvaine Cordier, George Davey-Smith, Brenda Eskenazi, David Gee, Kimberly Gray, Mark Hanson, Peter Van Den Hazel, Jerrold J. Heindel, Birger Heinzow, Irva Hertz-Picciotto, Howard Hu, Terry T.-K. Huang, Tina Kold Jensen, Phillip J. Landrigan, I. Caroline McMillen, Katsuyuki Murata, Beate RitzGreet Schoeters, Niels Erik Skakkebæk, Staffan Skerfving, Pal Weihe

    Research output: Contribution to journalArticlepeer-review

    209 Citations (Scopus)

    Abstract

    The periods of embryonic, foetal and infant development are remarkably susceptible to environmental hazards. Toxic exposures to chemical pollutants during these windows of increased susceptibility can cause disease and disability in infants, children and across the entire span of human life. Among the effects of toxic exposures recognized in the past have been spontaneous abortion, congenital malformations, lowered birthweight and other adverse effects. These outcomesmay be readily apparent. However, even subtle changes caused by chemical exposures during early development may lead to important functional deficits and increased risks of disease later in life. The timing of exposure during early life has therefore become a crucial factor to be considered in toxicological assessments.

    During 20 –24 May 2007, researchers in the fields of environmental health, environmental chemistry, developmentalbiology, toxicology, epidemiology, nutrition and paediatricsgathered at the International Conference on Fetal Programming and Developmental Toxicity, in Tórshavn, Faroe Islands. The conference goal was to highlight new insightsinto the effects of prenatal and early postnatal exposure tochemical agents, and their sustained effects on the individualthroughout the lifespan. The conference brought together researchers to focus on human data and the translation of laboratory results to elucidate the environmental risks to human health
    Original languageEnglish
    Pages (from-to)73-75
    Number of pages3
    JournalBasic and Clinical Pharmacology and Toxicology
    Volume102
    Issue number2
    Early online date30 Jul 2007
    DOIs
    Publication statusPublished - Feb 2008

    Keywords

    • environmental factors
    • Embryonic and Fetal Development
    • infant development
    • chemicals

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