Pre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine

John A Hartley, Michael J. Flynn, John P. Bingham, Simon Corbett, Halla Weihe Reinert, Arnaud Tiberghien, Luke A. Masterson, Dyeison Antonow, Lauren Adams, Sajidah Chowdhury, David G. Williams, Shenlan Mao, Jay Harper, Carin E.G. Havenith, Francesca Zammarchi, Simon Chivers, Patrick H van Berkel, Philip W. Howard

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Keyphrases

Pharmacology, Toxicology and Pharmaceutical Science

Medicine and Dentistry

Immunology and Microbiology