TY - JOUR
T1 - Potassium kinetics in human muscle interstitium during repeated intense exercise in relation to fatigue
AU - Mohr, Magni
AU - Nordsborg, Nikolai
AU - Nielsen, Jens Jung
AU - Pedersen, Lasse Danneman
AU - Fischer, Christian
AU - Krustrup, Peter
AU - Bangsbo, Jens
PY - 2004/3/27
Y1 - 2004/3/27
N2 - Accumulation of K+ in skeletal muscle interstitium during intense exercise has been suggested to cause fatigue in humans. The present study examined interstitial K+ kinetics and fatigue during repeated, intense, exhaustive exercise in human skeletal muscle. Ten subjects performed three repeated, intense (61.6±4.1 W; mean±SEM), one-legged knee extension exercise bouts (EX1, EX2 and EX3) to exhaustion separated by 10-min recovery periods. Interstitial [K+] ([K+]interst) in the vastus lateralis muscle were determined using microdialysis. Time-to-fatigue decreased progressively (P
AB - Accumulation of K+ in skeletal muscle interstitium during intense exercise has been suggested to cause fatigue in humans. The present study examined interstitial K+ kinetics and fatigue during repeated, intense, exhaustive exercise in human skeletal muscle. Ten subjects performed three repeated, intense (61.6±4.1 W; mean±SEM), one-legged knee extension exercise bouts (EX1, EX2 and EX3) to exhaustion separated by 10-min recovery periods. Interstitial [K+] ([K+]interst) in the vastus lateralis muscle were determined using microdialysis. Time-to-fatigue decreased progressively (P
KW - intermittent exercise
KW - anaerobic metabolism
KW - K_atp channels
KW - muscle acidosis
KW - microdialysis
UR - https://curis.ku.dk/portal/en/publications/potassium-kinetics-in-human-muscle-interstitium-during-repeated-intense-exercise-in-relation-to-fatigue(e212b8e0-ddf7-11db-bee9-02004c4f4f50).html
U2 - 10.1007/s00424-004-1257-6
DO - 10.1007/s00424-004-1257-6
M3 - Article
SN - 1432-2013
VL - 448
SP - 452
EP - 456
JO - Pflügers Archiv: European Journal of Physiology
JF - Pflügers Archiv: European Journal of Physiology
ER -