Neurobehavioral epidemiology: Application in risk assessment

Philippe Grandjean, Roberta F. White, Pal Weihe

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    Neurobehavioral epidemiology may contribute information to risk assessment in relation to a) characterization of neurotoxicity and its time course; b) the dose-effect relationship; c) the dose-response relationship; and d) predisposing factors. The quality of this information relies on the validity of the exposure data, the validity and sensitivity of neurobehavioral function tests, and the degree to which sources of bias are controlled. With epidemiologic studies of methylmercury-associated neurotoxicity as an example, the field of research involves numerous uncertainties that should be taken into account in the risk assessment process.
    Original languageEnglish
    Pages (from-to)397-400
    Number of pages4
    JournalEnvironmental Health Perspectives
    Issue number2
    Publication statusPublished - Apr 1996


    • Alcohol intake
    • Birth weight
    • Children
    • Confounding
    • Epidemiology
    • Lead
    • Marine food
    • Mercury
    • Neurobehavioral development
    • Neuropsychology
    • Pregnancy
    • Solvents


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