Microinjected Coxsackie B1 virus does not replicate in HEp-2 cell

Kristin R. Modalsli; Geir Bukholm; Svein-Ole Mikalsen; Miklos Degré

doi:10.1016/0042-6822(91)90566-t

Microinjected Coxsackie B1 virus does not replicate in HEp-2 cell

Kristin R. Modalsli, Geir Bukholm, Svein-Ole Mikalsen, Miklos Degré

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Coxsackie B1 virus did not replicate when microinjected into HEp-2 cells. Replication was assayed by production of infectious virus particles, synthesis of viral RNA, and lysis of cells. The same virus preparation initiated replication when it was inoculated into HEp-2 cells similarly to that by microinjected purified coxsackie B1 virus RNA.

Original language	English
Pages (from-to)	888-890
Number of pages	3
Journal	Virology
Volume	185
Issue number	2
DOIs	https://doi.org/10.1016/0042-6822(91)90566-t
Publication status	Published - 1991
Externally published	Yes

Keywords

Coxsackie B1 virus
viral replication
microinjection
Cell culture

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10.1016/0042-6822(91)90566-t

Cite this

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title = "Microinjected Coxsackie B1 virus does not replicate in HEp-2 cell",

abstract = "Coxsackie B1 virus did not replicate when microinjected into HEp-2 cells. Replication was assayed by production of infectious virus particles, synthesis of viral RNA, and lysis of cells. The same virus preparation initiated replication when it was inoculated into HEp-2 cells similarly to that by microinjected purified coxsackie B1 virus RNA.",

keywords = "Coxsackie B1 virus, viral replication, microinjection, Cell culture",

author = "Modalsli, {Kristin R.} and Geir Bukholm and Svein-Ole Mikalsen and Miklos Degr{\'e}",

year = "1991",

doi = "10.1016/0042-6822(91)90566-t",

language = "English",

volume = "185",

pages = "888--890",

journal = "Virology",

issn = "0042-6822",

publisher = "Elsevier Inc.",

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TY - JOUR

T1 - Microinjected Coxsackie B1 virus does not replicate in HEp-2 cell

AU - Modalsli, Kristin R.

AU - Bukholm, Geir

AU - Mikalsen, Svein-Ole

AU - Degré, Miklos

PY - 1991

Y1 - 1991

N2 - Coxsackie B1 virus did not replicate when microinjected into HEp-2 cells. Replication was assayed by production of infectious virus particles, synthesis of viral RNA, and lysis of cells. The same virus preparation initiated replication when it was inoculated into HEp-2 cells similarly to that by microinjected purified coxsackie B1 virus RNA.

AB - Coxsackie B1 virus did not replicate when microinjected into HEp-2 cells. Replication was assayed by production of infectious virus particles, synthesis of viral RNA, and lysis of cells. The same virus preparation initiated replication when it was inoculated into HEp-2 cells similarly to that by microinjected purified coxsackie B1 virus RNA.

KW - Coxsackie B1 virus

KW - viral replication

KW - microinjection

KW - Cell culture

U2 - 10.1016/0042-6822(91)90566-t

DO - 10.1016/0042-6822(91)90566-t

M3 - Article

SN - 0042-6822

VL - 185

SP - 888

EP - 890

JO - Virology

JF - Virology

IS - 2

ER -

Microinjected Coxsackie B1 virus does not replicate in HEp-2 cell

Abstract

Keywords

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