High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020

Malan Johansen; Kirsten Svenstrup; Poul Joensen; Bjarni á Steig; Guðrið Andorsdóttir; Torben Hansen; Maria Skaalum Petersen

High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020

Malan Johansen, Kirsten Svenstrup, Poul Joensen, Bjarni á Steig, Guðrið Andorsdóttir, Torben Hansen, Maria Skaalum Petersen

Deildin fyri heilsu- og sjúkrarøktarvísindi - Faculty of Health Sciences

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

29 Downloads (Pure)

Abstract

The Faroese population isolate harbors epidemiological and genetic characteristics that likely differ from outbred populations. This population-based register study found that the Faroese 2010–2020 crude incidence of amyotrophic lateral sclerosis (ALS) was 4.9/100,000 person-years (95% confidence interval [CI], 3.3–7.0) and the age- and sex-standardized incidence (US 2010 Census Population) was 4.1/100,000 person-years (95% CI, 2.7–6.0), which is a 68% increase from the 1987–2009 estimate. The 2020 crude prevalence was 9.5/100,000 (95% CI, 3.0–19.6) in a population of 52,912 inhabitants. Incidence and prevalence estimates of ALS in the Faroes are high and further research is warranted to uncover the genetic or environmental determinants of ALS in this population.

Original language	English
Pages (from-to)	227-231
Number of pages	5
Journal	Annals of Clinical and Translational Neurology
Volume	9
Issue number	2
Publication status	Published - 20 Jan 2022

Keywords

sclerosis
Faroe Islands
population-based register study
amyotrophic lateral sclerosis (ALS)

Access to Document

Johansen et al High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010 2020Final published version, 346 KBLicence: CC BY-NC-ND

https://onlinelibrary.wiley.com/doi/pdf/10.1002/acn3.51501Licence: CC BY-NC-ND

Cite this

@article{337b5b24321546ff87d878d80759b8a5,

title = "High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020",

abstract = "The Faroese population isolate harbors epidemiological and genetic characteristics that likely differ from outbred populations. This population-based register study found that the Faroese 2010–2020 crude incidence of amyotrophic lateral sclerosis (ALS) was 4.9/100,000 person-years (95% confidence interval [CI], 3.3–7.0) and the age- and sex-standardized incidence (US 2010 Census Population) was 4.1/100,000 person-years (95% CI, 2.7–6.0), which is a 68% increase from the 1987–2009 estimate. The 2020 crude prevalence was 9.5/100,000 (95% CI, 3.0–19.6) in a population of 52,912 inhabitants. Incidence and prevalence estimates of ALS in the Faroes are high and further research is warranted to uncover the genetic or environmental determinants of ALS in this population.",

keywords = "sclerosis, Faroe Islands, population-based register study, amyotrophic lateral sclerosis (ALS)",

author = "Malan Johansen and Kirsten Svenstrup and Poul Joensen and Steig, {Bjarni {\'a}} and Gu{\dh}ri{\dh} Andorsd{\'o}ttir and Torben Hansen and Petersen, {Maria Skaalum}",

year = "2022",

month = jan,

day = "20",

language = "English",

volume = "9",

pages = "227--231",

journal = "Annals of Clinical and Translational Neurology",

issn = "2328-9503",

publisher = "John Wiley & Sons Inc.",

number = "2",

}

TY - JOUR

T1 - High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020

AU - Johansen, Malan

AU - Svenstrup, Kirsten

AU - Joensen, Poul

AU - Steig, Bjarni á

AU - Andorsdóttir, Guðrið

AU - Hansen, Torben

AU - Petersen, Maria Skaalum

PY - 2022/1/20

Y1 - 2022/1/20

N2 - The Faroese population isolate harbors epidemiological and genetic characteristics that likely differ from outbred populations. This population-based register study found that the Faroese 2010–2020 crude incidence of amyotrophic lateral sclerosis (ALS) was 4.9/100,000 person-years (95% confidence interval [CI], 3.3–7.0) and the age- and sex-standardized incidence (US 2010 Census Population) was 4.1/100,000 person-years (95% CI, 2.7–6.0), which is a 68% increase from the 1987–2009 estimate. The 2020 crude prevalence was 9.5/100,000 (95% CI, 3.0–19.6) in a population of 52,912 inhabitants. Incidence and prevalence estimates of ALS in the Faroes are high and further research is warranted to uncover the genetic or environmental determinants of ALS in this population.

AB - The Faroese population isolate harbors epidemiological and genetic characteristics that likely differ from outbred populations. This population-based register study found that the Faroese 2010–2020 crude incidence of amyotrophic lateral sclerosis (ALS) was 4.9/100,000 person-years (95% confidence interval [CI], 3.3–7.0) and the age- and sex-standardized incidence (US 2010 Census Population) was 4.1/100,000 person-years (95% CI, 2.7–6.0), which is a 68% increase from the 1987–2009 estimate. The 2020 crude prevalence was 9.5/100,000 (95% CI, 3.0–19.6) in a population of 52,912 inhabitants. Incidence and prevalence estimates of ALS in the Faroes are high and further research is warranted to uncover the genetic or environmental determinants of ALS in this population.

KW - sclerosis

KW - Faroe Islands

KW - population-based register study

KW - amyotrophic lateral sclerosis (ALS)

M3 - Article

SN - 2328-9503

VL - 9

SP - 227

EP - 231

JO - Annals of Clinical and Translational Neurology

JF - Annals of Clinical and Translational Neurology

IS - 2

ER -

High incidence of amyotrophic lateral sclerosis in the Faroe Islands 2010–2020

Abstract

Keywords

Access to Document

Fingerprint

Cite this