Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)

Srdjan Djurovic; Stephanie Le Hellard; Anna K Kähler; Erik G Jönsson; Ingrid Agartz; Vidar M Steen; Håkan Hall; August G. Wang; Henrik Berg Rasmussen; Ingrid Melle; Thomas Werge; Ole A Andreassen

doi:10.1016/j.psychres.2008.08.007

Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)

Srdjan Djurovic, Stephanie Le Hellard, Anna K Kähler, Erik G Jönsson, Ingrid Agartz, Vidar M Steen, Håkan Hall, August G. Wang, Henrik Berg Rasmussen, Ingrid Melle, Thomas Werge, Ole A Andreassen

Deildin fyri heilsu- og sjúkrarøktarvísindi - Faculty of Health Sciences

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

The MCTP2 gene is involved in intercellular signal transduction and synapse function. We genotyped 37 tagging SNPs across the MCTP2 gene to study a possible association with schizophrenia in three independent Scandinavian samples. We report, for the first time, a possible involvement of MCTP2 as a potential novel susceptibility gene for schizophrenia.

Original language	English
Pages (from-to)	256-258
Number of pages	3
Journal	Psychiatry Research
Volume	168
Issue number	3
DOIs	https://doi.org/10.1016/j.psychres.2008.08.007
Publication status	Published - 15 Feb 2009

Keywords

female
gene frequency
genetic predisposition ti disease
genome-wide
association study
genotype
humans
male
membrane proteins
polymorphism
single nucleotide
Scandinavia
schizophrenia

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10.1016/j.psychres.2008.08.007

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Djurovic, S., Hellard, S. L., Kähler, A. K., Jönsson, E. G., Agartz, I., Steen, V. M., Hall, H., Wang, A. G., Rasmussen, H. B., Melle, I., Werge, T., & Andreassen, O. A. (2009). Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE). Psychiatry Research, 168(3), 256-258. https://doi.org/10.1016/j.psychres.2008.08.007

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abstract = "The MCTP2 gene is involved in intercellular signal transduction and synapse function. We genotyped 37 tagging SNPs across the MCTP2 gene to study a possible association with schizophrenia in three independent Scandinavian samples. We report, for the first time, a possible involvement of MCTP2 as a potential novel susceptibility gene for schizophrenia.",

keywords = "female, gene frequency, genetic predisposition ti disease, genome-wide, association study, genotype, humans, male, membrane proteins, polymorphism, single nucleotide, Scandinavia, schizophrenia",

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AU - Djurovic, Srdjan

AU - Hellard, Stephanie Le

AU - Kähler, Anna K

AU - Jönsson, Erik G

AU - Agartz, Ingrid

AU - Steen, Vidar M

AU - Hall, Håkan

AU - Wang, August G.

AU - Rasmussen, Henrik Berg

AU - Melle, Ingrid

AU - Werge, Thomas

AU - Andreassen, Ole A

PY - 2009/2/15

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AB - The MCTP2 gene is involved in intercellular signal transduction and synapse function. We genotyped 37 tagging SNPs across the MCTP2 gene to study a possible association with schizophrenia in three independent Scandinavian samples. We report, for the first time, a possible involvement of MCTP2 as a potential novel susceptibility gene for schizophrenia.

KW - female

KW - gene frequency

KW - genetic predisposition ti disease

KW - genome-wide

KW - association study

KW - genotype

KW - humans

KW - male

KW - membrane proteins

KW - polymorphism

KW - single nucleotide

KW - Scandinavia

KW - schizophrenia

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EP - 258

JO - Psychiatry Research

JF - Psychiatry Research

IS - 3

ER -

Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)

Abstract

Keywords

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